Pharmacodynamics ceftiofur ikirasi β -lactam yemishonga inorwisa mabhakitiriya, ine yakakura spectrum bactericidal chiito, inoshanda pakurwisa mabhakitiriya egiremu uye giremu-negative (kusanganisira β-lactamase inoburitsa mabhakitiriya). Iyo antibacterial maitiro ndeye kuvharira synthesis yebhakitiriya sero madziro uye kutungamirira kurufu rwebhakitiriya. Mabhakitiriya anonzwa anonyanya kunzi pasteurella multiplex, pasteurella hemolyticus, actinobacillus pleuropneumoniae, salmonella, escherichia coli, streptococcus, staphylococcus, etc. Mamwe pseudomonas aeruginosa, enterococcus resistant. Basa reantibacterial rechigadzirwa ichi rakasimba kupfuura iro reampicillin, uye basa rinopikisa streptococcus rakasimba kupfuura fluoroquinolones.
Pharmacokinetics ceftiofur inotorwa nekukurumidza uye zvakanyanya nemajekiseni emukati memuscular uye subcutaneous, asi haigone kuyambuka chipingamupinyi cheropa-uropi. Mushonga wemushonga wakakwirira muropa uye matishu, uye kushanda kweropa kunochengetwa kwenguva yakareba. Iyo inoshanda metabolite desfuroylceftiofur inogona kugadzirwa mumuviri, uye inowedzera metabolized kuita isingashande zvigadzirwa zvakaburitswa kubva muweti netsvina.
β-lactam antibiotics. Inonyanya kushandiswa kurapa zvirwere zvebhakitiriya zvezvipfuwo uye huku. Zvakadai senguruve bhakitiriya rekufema turakiti chirwere uye huku escherichia coli, salmonella utachiona.
Ceftofur inoshandiswa. Intramuscular jekiseni: Imwe dhigirii, 1.1- 2.2mg pa1kg uremu hwemombe, 3-5mg yemakwai nenguruve, 5mg yehuku nedhadha, kamwe pazuva kwemazuva matatu.
Subcutaneous jekiseni: 1-zuva-kare nhiyo, 0.1mg per feather.
(1) Inogona kukonzera gastrointestinal flora kusagadzikana kana kutapukira kaviri.
(2) Pane imwe nephrotoxicity.
(3) Kurwadza kwepanguva pfupi kunogona kuitika.
(1)Shandisa izvozvi.
(2) Mushonga unofanirwa kugadziriswa kune mhuka dzine renal insufficiency.
(3) Vanhu vane hanya zvikuru ne beta-lactam mishonga inorwisa mabhakitiriya vanofanira kudzivisa kusangana nechigadzirwa ichi uye kudzivisa kutarisana nevana.
