Pharmacodynamics flufenicol mushonga wakafaranuka mukirasi yeamidol, bacteriosuppressor, uye unoshanda nekusunga neribosome 50s subunit kuvharira kuumbwa kwemapuroteni ebhakitiriya. Iine simba rinorwisa mabhakitiriya rinopikisa zvakasiyana-siyana zve gram-positive uye gram-negative mabhakitiriya. Pasteurella hemolyticus, pasteurella multocida uye actinobacillus suis pleuropneumoniae vainzwa zvakanyanya neflufenicol. In vitro, basa reantimicrobial reflufenicol kurwisa tupukanana twakawanda rakafanana kana kuti rakasimba kupfuura re sulfenicol, uye mamwe mabhakitiriya anopokana neaminools nekuda kweacetylation, senge escherichia coli uye klebsiella pneumoniae, anogona kunge achiri kunzwa kune flufenicol.
Inonyanya kushandiswa kune zvirwere zvebhakitiriya zvenguruve, huku nehove zvinokonzerwa nebhakitiriya inonzwisisika, zvakadai sezvirwere zvekufema zvemombe nenguruve zvinokonzerwa ne pasteurella hemolyticus, pasteurella multocida uye actinobacillus pleuropneumoniae. Typhoid uye paratyphoid inokonzerwa nesalmonella, huku cholera, huku chena dysentery, colibacillosis, nezvimwewo; hove pasteurella, vibrio, staphylococcus aureus, hydroomonas, enteritis uye mamwe mabhakitiriya anokonzerwa nehove bhakitiriya septicemia, enteritis, erythroderma uye nokukurumidza.
1. Macrolides uye lincosamines vane chinangwa chakafanana nechigadzirwa ichi, ivo vanosanganiswa nebhakitiriya ribosome 50s subunit, uye inogona kuunza mhedzisiro inopikisa kana yabatanidzwa.
2. Inogona kupikisa basa rebhakitiriya repenicillin kana aminoglycosides, asi harina kuratidzwa mumhuka.
Amidoalcohol antibiotics, inonyanya kunzwisiswa nePasteurella hemolyticus, Pasteurella multocida uye actinobacillus pleuropneumoniae, inoshandiswa paPasteurella neEscherichia coli zvirwere.
Nechigadzirwa ichi. Nokuda kwehutungamiri hwemukati: 0.1 ~ 0.15g pa1kg yehuremu hwenguruve nehuku. 2 kanomwe pazuva kwemazuva matatu kusvika mashanu; 50 kusvika 75mg yehove. Shandisa kamwe chete pazuva kwemazuva matatu kusvika mashanu.
Kudyisa kwakasanganiswa: Ichi chigadzirwa 100g sanganisa 200 ~ 300kg, kushandiswa kunoramba kuripo kwemazuva 3 ~ 5.
1. Ichi chigadzirwa chine imwe immunosuppressive effect kana yakashandiswa yakakwirira kudarika inokurudzirwa dose.
2. Iine fetal toxicity, uye inofanira kushandiswa nekuchenjerera panguva yekuzvitakura nekuyamwisa zvipfuwo.
1. Nguva yekukandira yehuku haifanirwe kushandiswa.
2. Mhuka dzine simba rekudzivirira zvirwere zvakanyanya kana nguva yekudzivirira inofanira kurambidzwa.
3. Mhuka dzine renal insufficiency dzinofanira kuderedzwa zvakanaka kana kuwedzerwa nguva yekutonga nguva.
