Pharmacodynamics semi-synthetic macrolide antibiotics yeMhuka dzejenasi temicosin. Iyo yakasimba kune mycoplasma, uye iyo antibacterial effect yakafanana netylosin. Mabhakitiriya anonzwa magiremu ane staphylococcus aureus (kusanganisira penicillin-resistant staphylococcus aureus), pneumococcus, streptococcus, anthrax bacillus, swineerysipelas, listeria, clostridium putrefaciens, clostridium emphysema uye zvichingodaro. Sensitive gram-negative mabhakitiriya ane haemophilus, meningococci, pasteurella uye nokukurumidza. Basa rinopesana ne actinobacillus pleuropneumoniae, pasteurella uye mycoplasma yezvipfuwo nehuku yakasimba kudarika tylosin. 95% ye pasteurella hemolyticus strains yaive nehanya nechigadzirwa ichi.
Pharmacokinetic inokurumidza kubatwa mushure mekutonga kwemukati, inoratidzwa nekupinza kwenyama yakasimba, yakakura yakawanda yekugovera (yakakura kupfuura 2l / kg). Iko kusungirirwa kwakakwirira mumapapu, kubvisa hafu yehupenyu inogona kusvika 1 ~ 2 mazuva, uye kushanda kweropa kunoshanda kunochengetwa kwenguva yakareba.
(1) Kusanganiswa kwechigadzirwa ichi uye epinephrine kunogona kuwedzera kufa kwenguruve.
(2) Iine chinangwa chakafanana nemamwe macrolides uye lincoamines, uye haifaniri kushandiswa panguva imwe chete.
(3) Iko kusanganiswa kweβ-lactam kunoratidza kupokana.
Macrolide antibiotics. Inoshandiswa kurapa actinobacillus, pasteurella uye mycoplasma utachiona hweporcine pleuropneumoniae.
Kudya kwakasanganiswa: 1000 ~ 2000g yenguruve pa1000kg yekudya kwemazuva gumi nemashanu.
(1) Iyo muchetura mhedzisiro yechigadzirwa ichi pamhuka inonyanya kukonzeresa moyo, izvo zvinogona kukonzera tachycardia uye kunetesa systolic simba.
(2) Dose-inotsamira gastrointestinal kusagadzikana, sekurutsa, manyoka, kurwadziwa mudumbu, nezvimwewo, zvinowanzoitika mushure mekutonga kwemukati.
